Game Tips, Strategy Guides, Walkthroughs

Bacterial Takeover Guide, Useful Game Tips and Tricks

The day and age is unknown. You are a lone scientist, in your secret laboratory. Fueled by rage, with reasons only known to you, you set out to conquer and destroy every known planet that you are able to get your hands on. Using only bacteria and different variations and strains of said bacteria, you need to cultivate, upgrade, and unleash your millions and billions of little minions, destroying planets one at a time and bask in the destruction of life.

Bacterial Takeover Tips and Strategy Guide

Bacterial Takeover is a very simplistic game, with a fun adaptation around the tap-centric grinders that are constantly being put out. Instead of attempting to win over a group of businesses, or buy out buildings and hotels, you are attempting to completely wipe out existences on planets within and outside of our solar system. Starting with just a little bit of bacteria, you must use your finger to create bacteria, as well as buy such things as petri dishes and trash cans that allow you to passively create more bacteria when you are at your desk creating the bacteria, or sleeping under the desk. Here are some tips and tricks to ensure you are able to make the most out of your time producing bacteria, and make sure you one-shot every planet you go to.

  1. Build up enough so you only need to attack once. One of the big differences between this game and others is that, the resource that you use to produce greater production factories is also the same resource that you use to attack the planets. This causes some confusion for players as they seem hesitant on letting the factories grow on their own to a certain degree, or continuously spending the bacteria on upgrades. In the end, continuously spending your bacteria for new upgrades creates the fastest possible production speed per planet. If you do attack more than once, you end up completely losing all your progress, which means you have to start from scratch. The only possible good thing that could come from attacking to down a population a bit would be to gather gene strands, but since most upgrades cost 100-200 per, it’s better to just kill a whole planet off at once, instead of multiple strikes.
  2. Focus on passive production rather than active. Between tapping upgrades and passive upgrades, such as petri dishes and such, upgrading passive production items will give you immense benefits. Not only will they increase production rates, after buying a certain amount of each passive production unit, they grant special boosts that will boost their overall output by a certain percentage. Usually, these are around 200% per upgrade of the production item itself. With this, you can easily start gaining crazy amounts of bacteria at a much faster rate, especially when you add in gene strand upgrades.
  3. Focus on production gene strand upgrades that improve production of passive creation. With gene strands, you have the possibility of upgrading many different production methods. Mainly, you will have the choice if you wish to increase the BPC count, or the BPS count. BPS stands for bacteria per second, and they are the upgrades that you want to go for in terms of outputting. Most of the time, you want to focus on the skills that allow for overall BPS production increases, meaning the more bacteria passive production you have going on, the more it will give you in return.
  4. When researching DNA, go for the full 24 hours for greatest possible discovery. DNA research is the big breaking point which you unlock after beating the first planet to a pulp. When you first unlock the ability, you are able to research new tech, or basically attempt to discover new DNA strands that will give you significant bonuses to your productions. Each discovery process has a time limit and a percentage chance to discover attached to it. For full chance optimization, I always say do the 50% chance discovery. Doing this allows you to always have a 50% chance to discover a new strain, obviously, but it also only takes a few hours. For this reason, in terms of time consumption as well as output received, it’s a great deal.
  5. Always click on the red bacteria, maybe watch an ad or two. Now, generally I don’t talk about these kinds of things, since I generally disprove of them. But, in the game, sometimes you’ll find a red bacteria swimming around. These red bacteria are special and very rare, and will give you certain limited time boosts, such as increasing your BPS by many times. Clicking on them are beneficial, and only appear when you are actively playing. Now, sometimes they will ask for you to watch an ad for extra Bacteria. For this, I would say do it. This is due to the fact that it allows you to utilize that time that you would be tapping away, and gives you a short ad and grants you many more Bacteria than what you would get just tapping. Thus, using these are a great way to constantly increase your Bacteria Points.

These are just a few of the tips for Bacteria Takeover. But, you can play however you’d like. If you found these helpful, let me know, and if you didn’t, well good luck to you! Good luck, and happy destruction!



21 thoughts on “Bacterial Takeover Guide, Useful Game Tips and Tricks”

  • The first tip seems suitable only for the first 3 planets. Next planets are too overpopulated, so you can’t really beat them with one attack. It’s much more efficient to beat a half or a third and get some gene strands that will boost you. Just my thoughts.

    • you clearly dont understand what hes saying. hes simply saying if you can then attack to kill all. but if you need the strands (meaning if the strands added will double your gain in the same amount of time) then attack to gain those strands becauae its obvious that those strands are more important than getting a 1 hit ender.

      • All 8 planets ive got are 1 hit. Gain achievements and take ur time. No speed requirements in a tap game right?

  • @John Doe

    I am currently on planet 10. All planets have been wiped out in one attack each. Remember that when you attack, resistance builds and makes the next attack much harder. Let’s say it takes 1M bacteria to kill 10% of the population. The next attack at 1M bacteria will not kill 10%.

    Remember that.

  • Taking the 24 hour DNA search depends on how many times you can play per day, and at what interval:
    1x24h = 1x 75% => you have an expected value of 0.75
    15x15min = 15x 5% also gives you an expected value of 0.75
    8x1h = 8×10% gives you an expected value of 0.80
    3x6h = 3×0.3 gives you an expected value of 0.9

    So first, if you can play many times a day, it is statistically favourable to take smaller values, and second, every time you fail a research you get bacterias.

      • Is it not? The expected value with discrete values in a case like this is just the sum of the probability times the weighting. For example, for the 15 minute one, each time you have a 5% chance of getting a success, so your expected value is 0.05 over 15 minutes, if you do this 15 times, so 3 hrs 45 mins, you would get an expected value of 0.05+0.05+0.05… = 15*0.05 = 0.75, so an expected value of 0.75 in 3 hrs 45 mins vs an expected value of 0.75 in 24 hrs.
        I think you were thinking about the PROBABILITY of getting a success over x amount of time, not the EXPECTED VALUE of # of successes, which is, essentially, the average number of bacteria you would get in x amount of time, rather than the chance of getting a success in x amount of time.

        • Alright man,
          your math is way of. By your logic, that’d mean if you do a 15% 20 times then you’d be assured. Obviously not the case. you use the formulas P = 1-Q, where Q is the Probability of the event not Happening, and P is of it happening. Q in this case would be Q1^n. So doing something with if you do something 15 times with the Probability of success as 15% it’s P = 1- (0.75^15)= .986. So actually better than you thought.

          • no, by his logic after doing 5% 20 times he would EXPECT to get one upgrade.. that’s the definition of EXPECTED value.

            His math is valid.

            In reality he may get it 20 times if he does 5% 20 times in a row, but this is highly unlikely.. however, if he does it 20 trillion times, i would EXPECT the number of upgrades to indeed be very close to 1 trillion.

      • U both have valid points but looking at it differently i think. Very well said by both and i appreciate the viewpoints. I feel like i learned sumthing thank u

  • I’m at planet 25… you can’t kill planets in 1 single hit sometimes.. stop the effort. Go to the max prod you can and just attack. Its very fast and very efficient. I’m literally at 2trillion gene strands at the moment and i cant kill planets in 1 turn atm. Everything is maxed. Active tapping is like 50 times better than my passive.. remember that 😉 passive might be important but man.. that active is way better!

  • it’s easy to cheat in this game, just go into your phone settings and change the day to tomorrow, and switch back to the game. You’re welcome.

      • Well said, thats been an option since apps were made consisting of time based bonuses. Id rather wait, i dont make money for attacking simulated atmospheres

    • I downloaded this game last night and less than 24 hours into it ive already destroyed 29 planets. The black hole formation has been at 100% for like 10 planets too but hasnt done anything. I have 9 rare/epic strains at level 3.

      Anyone know when the black hole actually does whatever it is supposed to do?

  • I completely beat this game killed every planet they had at that given loint in time with the new update i get to destroy more planets so i decided tl completely restart the game amd i have started to figure alot more things out about fastest ways to upgrade and buy item if you make it to where the most expensive item is maxed and you make sure its atleast at 100 or more u start at the bottom and work your way up at one loint in time i had close go 10k of each dish you gotta plan ahead and the more bacteria you have when you destroy a planet the more gene strands u will recieve

  • Wow this guide must be from before black hole because half of it is not valid anymore.
    1. The one hit is near impossible at planets after 35. I’d estimate it takes years of production for something like planet 43. On the other hand it takes 60+ attacks with nanobots saving your day in the end. But before nanobots are any gid you need to reduce the% of the planet below 1%.
    2. Production doubling makes no sense in late game. Even if you get 100%chance it’s still 1 out of 15 chance of getting you best colony and that is the only one that matters. Get the production doubling per idle researcher instead from the black hole.
    3. Gene Strand upgrades don’t matter much when you got e+7 or more. They might speed up you first 30 seconds of playing after attacking a planet abs that’s it. On the other hand the”loss”of gene strands is minimal. So get them all or not it’s up to you and doesn’t really matter in late game.
    Anyway good luck all players and enjoy playing.
    Hope they release another update soon.

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